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Cryo-EM @ Harvard Medical School

Two core facilities currently available to qualified researchers in the HMS community

B04 & B032 Seeley G. Mudd, 250 Longwood Ave, Boston MA 02115

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Blog

The K2 direct detector is currently being installed on the Arctica

July 11, 2018

ArcticaK2

Time-Lapse Video of the Arctica Installation!

June 4, 2018

Krios #2 following a few days later...

May 31, 2018

krios...

Read more about Krios #2 following a few days later...

Krios #1 is here!

May 29, 2018

Krios #1 was delivered today :

Riggers...

Read more about Krios #1 is here!

Prepping for Krios delivery

May 23, 2018

Assmebling the boxes for Krios #1 and Krios #2

krios1...

Read more about Prepping for Krios delivery

Look at that Arctica glow...

May 9, 2018

Far from ready but the connections have been made and power is flowing to the Arctica!Arctica

The Talos Arctica has arrived!

May 2, 2018

Newly placed in the room:

Gun chamber to be added to the top of the column:

...

Read more about The Talos Arctica has arrived!

New floors, walls painted and doors hung...just a few weeks before the Arctica arrives!

April 5, 2018

room

Installation of the first vibration platform

March 19, 2018

platform

Walls are up and are being finished with plywood, aluminum shielding and drywall...

January 31, 2018

Shielding... Read more about Walls are up and are being finished with plywood, aluminum shielding and drywall...
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Follow us at Twitter.com/HC2EM

  • RPNowak
    RPNowak Structural basis of regulated m7G tRNA modification by METTL1–WDR4. It was great to be part of this Gregory Lab - @fischerlab1 collaboration. With amazing Jiazhi Li, @ssroyburman @HongYue88665668 @moritzhunkeler @HC2EM. #METTL1 #WDR4 #tRNA #Xray #cryoEM t.co/nTFmSQrkOt
    2 weeks 9 hours ago.
  • thechaolab
    thechaolab big thanks to the team: @michelleyfry @Navarro_PaulaP @VirlyAnanda5 @MakhloutaLugo @puspannehakim Bridget Luce, @fanfanYG @jlmcd_
    2 weeks 1 day ago.
  • WuLabHarvard
    WuLabHarvard So excited that we finally have the ACTIVE NLRP3 inflammasome structure, thanks to super talented Le Xiao @LeXiao17, and Venkat Magupalli @MagupalliVenny! t.co/gUJA8QH5Kv t.co/CAJVbU1vu3
    2 months 4 days ago.
  • BobbyHollings
    BobbyHollings @LeXiao17 solves the structure of the NLRP3 inflammasome with a tour de force purification and reconstitution strategy--bravo!! t.co/sK7xB3QDkw
    2 months 5 days ago.
  • cryoEM_Papers
    cryoEM_Papers Cryo-EM structures of the active NLRP3 inflammasome disk t.co/mZt0C3Za0v
    2 months 5 days ago.
  • JoeLoparo
    JoeLoparo Our first paper investigating the mechanism of the bacterial cell wall machinery. In this collaborative work with the Kruse and Bernhardt labs, we show how conformational dynamics of RodA-PBP2 coordinate its enzymatic activities. t.co/SnwZ8p4kF0
    2 months 2 weeks ago.
  • BlacklowLab
    BlacklowLab Check out the @ColinLipper pre-print - Structural Basis for Selective Proteolysis of ADAM10 Substrates at Membrane-Proximal Sites t.co/y551IhU758
    3 months 1 week ago.
  • RachelleGaudet
    RachelleGaudet @HHMINEWS Gilliam Fellow @JoseAVelilla2's beautiful structures of ClbP are out! Exciting collaboration with @BalskusLab, including @MatthewRVolpe and Grace Kenney, and Richard Walsh from @HC2EM helping with our first cryo-EM structure! More in thread (1/6) t.co/sud8FFIT4y
    3 months 2 weeks ago.
Click to go to Twitter.com/HC2EM
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Harvard Cryo-EM Center
for Structural Biology
B04 Seeley G. Mudd
250 Longwood Ave
Boston, MA 02115
Molecular Electron
Microscopy Suite
B032 Seeley G. Mudd
250 Longwood Ave
Boston, MA 02115

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