Harvard Medical School has released information about the re-entry process and Phase I of the re-opening will begin on Monday, June 8th. Re-opening strategies for the Molecular EM Suite and Harvard Cryo-EM Center have been reviewed and approved, but are subject to change as more guidelines are released. We will keep our strategies for facility re-opening updated on the website and will send an email to our user list if major modifications are made. During Phase I, we will only allow COVID-19 related work in both facilities, with the exception of pre-arranged grid drop-off in the Harvard Cryo-EM Center. All new projects (COVID-19 and non-COVID-19 work) in the Harvard Cryo-EM Center should submit a project proposal to be reviewed per our normal process. Our COVID-19 page provides the latest information about the facilities.
The Harvard Cryo-Electron Microscopy Center for Structural Biology is a joint effort by Harvard Medical School, Dana-Farber Cancer Institute, Boston Children’s Hospital, and Massachusetts General Hospital to provide state-of-the-art cryo-EM instrumentation and expertise for the Harvard structural biology community. This user facility offers consultation and training by staff in specimen preparation, microscope operation, image acquisition, and data analysis. Currently, two MarkIV Vitrobots for sample preparation are available for use and we are accepting new users for the Talos Arctica and Titan Krios microscopes. The facility houses two Titan Krios election microscopes and a Talos Arctica electron microscope, all equipped with Gatan K3 Summit direct electron detectors.
Additionally, the Molecular Electron Microscopy Suite at Harvard Medical School is a separate user resource currently available to qualified researchers affiliated with Quad-based labs at HMS. This separate resource offers training and supervision in negative-stain and cryo-transmission electron microscopy. Equipment includes four transmission electron microscopes, two cryo plungers, and sample preparation areas. The Tecnai F20 and Polara F30 TEMs are each equipped with Gatan K2 Summit direct electron detectors.
If you have questions about access, services, or training, please email us at firstname.lastname@example.org.