#  Cryo-EM Center  

 



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The **Harvard Cryo-Electron Microscopy Center for Structural Biology (HC2EM)** is a joint effort by Harvard Medical School, Dana-Farber Cancer Institute, Boston Children’s Hospital, Massachusetts General Hospital and Harvard University to provide state-of-the-art cryo-EM instrumentation and expertise for the Harvard structural biology community. We are located on the Harvard Medical School campus in the basement of the Seeley G. Mudd building at: Room B04 250 Longwood Avenue, Boston MA 02115.

Currently, two MarkIV Vitrobots for sample preparation are available for use and we are accepting new users for the Talos Arctica and Titan Krios microscopes. The facility houses two Titan Krios election microscopes and a Talos Arctica electron microscope. This user facility offers consultation and training by staff in specimen preparation, microscope operation, image acquisition, and data analysis.

**Please contact** [**cryoem@crystal.harvard.edu**](mailto:cryoem@crystal.harvard.edu) **with any specific questions.**