Greetings to you all! We hope you are staying safe and healthy during these challenging times. Here's an update about how the Cryo-EM Center and the MEMS have been running during the shutdown.
Richard and Sarah have been rotating weeks on-site to clip and load samples and keep the microscopes cooled and aligned in the Cryo-EM Center. The on-site person has also been responsible for maintaining the disinfection routine we put in place on March 18th. Think about how many knobs, mice, keyboards, etc. you have to touch when you use a...
LiudmilaLANExcited to share our work about discovering a novel NLRP3 oligomeric state in a form of a double ring cage! t.co/X50XcmEg4F
Our findings show that unlike other inflammasome sensors, endogenous full-length NLRP3 is not monomeric, but forms a membrane-associated double ring
sshaolabCheck out this potent cycloheximide derivative made and characterized by the @liaulab! A fun collaboration that made us think hard about RPF positions and learn how chemistry journals are not at all like biology ones. t.co/T9YAe1g0D2